{"id":35,"date":"2016-05-15T22:35:06","date_gmt":"2016-05-15T20:35:06","guid":{"rendered":"http:\/\/zimp.umed.pl\/?page_id=35"},"modified":"2023-05-13T15:16:24","modified_gmt":"2023-05-13T13:16:24","slug":"rafal-pawliczak","status":"publish","type":"page","link":"https:\/\/zimp.umed.pl\/index.php\/pracownicy\/rafal-pawliczak\/","title":{"rendered":"Prof. dr hab. n. med. Rafa\u0142 Pawliczak"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-373\" src=\"http:\/\/zimp.umed.pl\/wp-content\/uploads\/pobrane-300x199.jpg\" alt=\"prof. dr hab. n. med. Rafa\u0142 Pawliczak\" width=\"412\" height=\"273\" srcset=\"https:\/\/zimp.umed.pl\/wp-content\/uploads\/pobrane-300x199.jpg 300w, https:\/\/zimp.umed.pl\/wp-content\/uploads\/pobrane-1024x678.jpg 1024w, https:\/\/zimp.umed.pl\/wp-content\/uploads\/pobrane.jpg 1280w\" sizes=\"auto, (max-width: 412px) 100vw, 412px\" \/><\/p>\n<p><strong>Kontakt<\/strong><\/p>\n<p>rafal.pawliczak@csk.umed.lodz.pl<\/p>\n<p><strong>Wykszta\u0142cenie<\/strong><\/p>\n<ul>\n<li>1993 \u2013dyplom z wyr\u00f3\u017cnieniem i tytu\u0142 zawodowy lekarza, Uniwersytet Medyczny w \u0141odzi<\/li>\n<li>1999 \u2013 doktor nauk medycznych, Wydzia\u0142 Lekarski, Akademia Medyczna w \u0141odzi<\/li>\n<\/ul>\n<p>Tytu\u0142 pracy: <em>,,Por\u00f3wnanie metabolizmu kwasu arachidonowego w hodowlach kom\u00f3rek nab\u0142onk\u00f3w g\u00f3rnych dr\u00f3g oddechowych u chorych na astm\u0119 z nadwra\u017cliwo\u015bci\u0105 na aspiryn\u0119 i u os\u00f3b dobrze toleruj\u0105cych niesteroidowe leki przeciwzapalne\u2019\u2019<\/em><\/p>\n<ul>\n<li>2003 \u2013 doktor habilitowany nauk medycznych, Wydzia\u0142 Lekarski, Uniwersytet Medyczny w \u0141odzi<\/li>\n<\/ul>\n<p>Tytu\u0142 pracy: <em>,,Znaczenie ekspresji bia\u0142ka p11 i cytozolowej fosfolipazy A<sub>2<\/sub> w mechanizmach wewn\u0105trzkom\u00f3rkowej regulacji odpowiedzi zapalnej w drogach oddechowych\u2019\u2019<\/em><\/p>\n<ul>\n<li>2009 \u2013 tytu\u0142 Profesor nauk medycznych<\/li>\n<\/ul>\n<p><strong>Specjalizacje<\/strong><\/p>\n<ul>\n<li>1999 \u2013 Choroby wewn\u0119trzne I<\/li>\n<li>2005 \u2013 Choroby wewn\u0119trzne II<\/li>\n<li>2007 \u2013 Alergologia<\/li>\n<\/ul>\n<p><strong>Zagraniczne sta\u017ce naukowe<\/strong><\/p>\n<p>1999-2002 John E. Fogarty International Postdoctoral Fellowship, National Institute of Health (NIH), Bethesda, USA<\/p>\n<p><strong>Szkolenia<\/strong><\/p>\n<ul>\n<li>2017 &#8211; szkolenie z zakresu edukacji medycznej\u00a0\u00a0<strong><a href=\"http:\/\/zimp.umed.pl\/wp-content\/uploads\/CEdMed_16-17_Rafal-Pawliczak.pdf\">Metodyka Nauczania w Dyscyplinach Biomedycznych<\/a><\/strong><\/li>\n<\/ul>\n<p><strong>Nagrody i wyr\u00f3\u017cnienia<\/strong><\/p>\n<p><em>Krajowe:<\/em><\/p>\n<ul>\n<li>Nagroda Rektora &#8211; naukowa II stopnia za publikacj\u0119<\/li>\n<\/ul>\n<p style=\"padding-left: 30px;\">Wieczfinska J, Pawliczak R. <em>Thymic stromal lymphopoietin and apocynin alter the expression of airway remodeling factors in human rhinovirus-infected cells.\u00a0<\/em>Immunobiology.\u00a02017 Aug;222(8-9):892-899.<\/p>\n<ul>\n<li>Nagroda Rektora &#8211; naukowa II stopnia za publikacj\u0119<\/li>\n<\/ul>\n<p style=\"padding-left: 30px;\">Luczak E, Wieczfinska J, Sokolowska M, Pniewska E, Luczynska D, Pawliczak R. <em>Troglitazone, a PPAR-\u03b3 agonist, decreases LTC4 concentration in mononuclear cells in patients with asthma.\u00a0<\/em>Pharmacol Rep.\u00a02017 Dec;69(6):1315-1321.<\/p>\n<ul>\n<li>Nagroda Rektora &#8211; naukowa II stopnia za publikacj\u0119<\/li>\n<\/ul>\n<p style=\"padding-left: 30px;\">\u00a0Juczynska K, Wozniacka A, Waszczykowska E, Danilewicz M, Wagrowska-Danilewicz M, Wieczfinska J, Pawliczak R, Zebrowska A. <em>Expression of the JAK\/STAT Signaling Pathway in Bullous Pemphigoid and Dermatitis Herpetiformis.\u00a0<\/em>Mediators Inflamm<a title=\"Mediators of inflammation.\" role=\"menuitem\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Expression+of+the+JAK%2FSTAT+Signaling+Pathway+in+Bullous+Pemphigoid+and+Dermatitis+Herpetiformis.#\" aria-expanded=\"false\" aria-haspopup=\"true\">.<\/a>\u00a02017;2017:6716419.<\/p>\n<ul>\n<li>2017 &#8211; Nagroda Rektora dla nauczycieli akademickich za osi\u0105gni\u0119cia uzyskane 2016 roku &#8211; II stopnia\u00a0za publikacj\u0119<\/li>\n<\/ul>\n<p style=\"padding-left: 30px;\">Kleniewska P,\u00a0Hoffmann A,\u00a0Pniewska E,\u00a0Pawliczak R.\u00a0<em>The Influence of Probiotic Lactobacillus casei in Combination with Prebiotic Inulin on the Antioxidant Capacity of Human Plasma.\u00a0<\/em>Oxid Med Cell Longev.\u00a02016;2016:1340903.<\/p>\n<ul>\n<li>2014 &#8211; Nagroda Rektora dla\u00a0nauczycieli akademickich za osi\u0105gni\u0119cia uzyskane 2013 roku &#8211; II stopnia\u00a0za publikacj\u0119<\/li>\n<\/ul>\n<p style=\"padding-left: 30px;\">Wieczfinska\u00a0J,\u00a0Sokolowska M,\u00a0Pawliczak R.\u00a0<em>NOX Modifiers-Just a Step Away from Application in the Therapy of Airway Inflammation?<\/em>\u00a0Antioxid Redox Signal.2015 Aug 10;23(5):428-45.<\/p>\n<ul>\n<li>2014 &#8211;\u00a0Nagroda Rektora dla\u00a0 nauczycieli akademickich za osi\u0105gni\u0119cia uzyskane 2013 roku &#8211; za pomys\u0142 i redakcj\u0119 ksi\u0105\u017cki &#8222;Alergologia &#8211; kompedium&#8221; wyd. Termedia 2013, Wydanie I<\/li>\n<li>2012 &#8211;\u00a0 Nagroda Rektora dla\u00a0 nauczycieli akademickich za osi\u0105gni\u0119cia uzyskane 2011 roku &#8211;\u00a0Nagroda zespo\u0142owa naukowa I stopnia za cykl publikacji:&#8221;Genetyczne, \u015brodowiskowe i molekularne uwarunkowania chor\u00f3b nowotworowych i zapalnych sk\u00f3ry&#8221;<\/li>\n<li>2009 &#8211; Nagroda Polskiego Towarzystwa Statystycznego za promotorstwo pracy doktorskiej dr Tomasza Adamusiaka<\/li>\n<li>2006 &#8211; Nagroda Ministra Zdrowia za publikacje<\/li>\n<li>2005 \u2013 Nagroda Polskiego Towarzystwa Alergologicznego za najlepszy abstrakt<\/li>\n<li>2005 &#8211; Nagroda Premiera RP za\u00a0<a href=\"https:\/\/pl.wikipedia.org\/wiki\/Habilitacja\">rozpraw\u0119 habilitacyjn\u0105<\/a><\/li>\n<li>1998 \u2013 Nagroda Fundacji Stefana Batorego<\/li>\n<li>1996 &#8211; Stypendium Fundacji im. Jakuba hr. Potockiego, pobyt w Royal London Hospital<\/li>\n<\/ul>\n<p><em>Zagraniczne:<\/em><\/p>\n<ul>\n<li>2003 \u2013 Silver Travel Grant of European Respiratory Society<\/li>\n<li>2003 \u2013 Scholarship of the European Academy of Allergy and Clinical Immunology<\/li>\n<li>1998 \u2013 European Academy of Allergy and Clinical Immunology Travel Grant<\/li>\n<li>1997 \u2013 The Upjohn Pharmacia and Education Grant<\/li>\n<li>1997 \u2013 European Respiratory Travel Grant<\/li>\n<li>1997 \u2013 European Respiratory Travel Grant<\/li>\n<\/ul>\n<p><strong>Publikacje<\/strong><\/p>\n<ol>\n<li><span class=\"authors\">Kopa-Stojak P, Pawliczak R.<\/span> <span class=\"art_title\">Comparison of effects of tobacco cigarettes, electronic nicotine delivery systems and tobacco heating products on miRNA-mediated gene expression. A systematic review,<\/span>\u00a0<span class=\"serial_title\">Toxicology Mechanisms and Methods,<\/span> <span class=\"date\">(2023); <\/span><span class=\"volume_issue\">33:1.<\/span><\/li>\n<li>Kowalczyk T, Sitarek P, \u015aliwi\u0144ski T, Hatziantoniou S, Soulintzi N, Pawliczak R, Wieczfinska J. New Data on Anti-Inflammatory and Wound Healing Potential of Transgenic\u00a0<i>Senna obtusifolia<\/i>\u00a0Hairy Roots: In Vitro Studies.\u00a0<em>International Journal of Molecular Sciences<\/em>. 2023; 24(6):5906.<\/li>\n<li>Tatka A, Pawliczak R. Skin manifestations associated with COVID-19. Alergologia Polska &#8211; Polish Journal of Allergology. 2022;9(3):143-149.<\/li>\n<li>Tatka A, Pawliczak R. The role of diet in atopic dermatitis. Alergologia Polska &#8211; Polish Journal of Allergology. 2022;9(2):99-105.<\/li>\n<li>Sitarek P, Kowalczyk T, \u015aliwi\u0144ski T, Hatziantoniou S, Soulintzi N, Pawliczak R, Wieczfinska J.\u00a0<i>Leonotis nepetifolia<\/i>\u00a0Transformed Root Extract Reduces Pro-Inflammatory Cytokines and Promotes Tissue Repair In Vitro.\u00a0<em>International Journal of Environmental Research and Public Health<\/em>. 2023; 20(6):4706.<\/li>\n<li><span class=\"author\">Wieczfinska, J<\/span>,\u00a0<span class=\"author\">Sitarek, P<\/span>,\u00a0<span class=\"author\">Kowalczyk, T<\/span>,\u00a0<span class=\"author\">Rieske, P<\/span>,\u00a0<span class=\"author\">Pawliczak, R<\/span>.\u00a0<span class=\"articleTitle\">Curcumin modulates airway remodelling-contributing genes\u2014the significance of transcription factors<\/span>.\u00a0<i>J Cell Mol Med<\/i>.\u00a0<span class=\"pubYear\">2022<\/span>;\u00a0<span class=\"vol\">26<\/span>:\u00a0<span class=\"pageFirst\">736<\/span>\u2013\u00a0<span class=\"pageLast\">749<\/span>.<\/li>\n<li>Wieczfinska J, Pawliczak R. Relaxin Affects Airway Remodeling Genes Expression through Various Signal Pathways Connected with Transcription Factors.\u00a0<em>International Journal of Molecular Sciences<\/em>. 2022; 23(15):8413.<\/li>\n<li>Pawliczak R, Emeryk A, Kupczyk M, Chorostowska-Wynimko J, Kuna P, Kulus M. Guidelines for asthma diagnosis and treatment Polish Society of Allergology, Polish Society of Lung Diseases and Polish Society of Family Medicine (STAN3T). Alergologia Polska &#8211; Polish Journal of Allergology. 2023;10(1):1-14.<\/li>\n<li>Lorenz D, Pawliczak R. Oral anti-COVID-19 drugs that were recently evaluated by FDA or EMA: a review. Alergologia Polska &#8211; Polish Journal of Allergology. 2022;9(1):33-40.<\/li>\n<li>Nowak A, Pawliczak R. Cigarette smoking and oxidative stress. Alergologia Polska &#8211; Polish Journal of Allergology. 2022;9(2):89-98.<\/li>\n<li>Kleniewska, P., Pawliczak, R. Does Oxidative Stress Along with Dysbiosis Participate in the Pathogenesis of Asthma in the Obese?.\u00a0<i>Cell Biochem Biophys<\/i>\u00a081, 117\u2013126 (2023).<\/li>\n<li>Hoffmann A, Str\u00f3zik T, Wasiak T, Buczy\u0142ko K, Pawliczak R. Compositional differences between gut microbiota of adult patients with asthma and healthy controls. Advances in Dermatology and Allergology\/Post\u0119py Dermatologii i Alergologii. 2023;40(1):142-149.<\/li>\n<li>Skalska M, Kleniewska P, Pawliczak R. Participation of reactive oxygen species in the pathogenesis of atopic dermatitis, allergic rhinitis and asthma. Alergologia Polska &#8211; Polish Journal of Allergology. 2023;10(1):26-31.<\/li>\n<li>Wieczfinska J, Kleniewska P, Pawliczak R. Oxidative Stress-Related Mechanisms in SARS-CoV-2 Infections&#8221;, <i>Oxidative Medicine and Cellular Longevity<\/i>, vol. 2022, Article ID 5589089, 15 pages, 2022.<\/li>\n<li>Sobczak M, Pawliczak R. Does Vitamin D Work Synergistically with Anti-Asthmatic Drugs in Airway Remodeling?\u00a0<em>International Journal of Molecular Sciences<\/em>. 2022; 23(21):12798.<\/li>\n<li>Sobczak M, Pawliczak R. Factors That Affect the COVID-19 Pandemic in Summer 2022 Compared to Summer 2021.\u00a0<em>International Journal of Environmental Research and Public Health<\/em>. 2022; 19(19):12561.<\/li>\n<li>Sobczak, M., Pawliczak, R. COVID-19 vaccination efficacy in numbers including SARS-CoV-2 variants and age comparison: a meta-analysis of randomized clinical trials.\u00a0<i>Ann Clin Microbiol Antimicrob<\/i>\u00a021, 32 (2022).<\/li>\n<li>Sobczak, M., Pawliczak, R. COVID-19 mortality rate determinants in selected Eastern European countries.\u00a0<i>BMC Public Health<\/i>\u00a022, 2088 (2022).<\/li>\n<li>Sobczak M, Pawliczak R. The risk of anaphylaxis behind authorized COVID-19\u00a0vaccines: a meta-analysis. Clin Mol Allergy. 2022 Jan 17;20(1):1.<\/li>\n<li>Wieczfinska J, Sitarek P, Kowalczyk T, Rieske P, Pawliczak R. Curcumin\u00a0modulates airway remodelling-contributing genes-the significance of\u00a0transcription factors. J Cell Mol Med. 2021 Dec 23.<\/li>\n<li>Nowak A, Pawliczak R. Comparison of the harmfulness of smoking tobacco cigarettes versus heat-not-burn tobacco in patients with asthma. Alergologia Polska &#8211; Polish Journal of Allergology. 2021;8(2):72-76.<\/li>\n<li>Pietrusiewicz M, Kopa-Stojak PN, Pawliczak R. Pharmacist&#8217;s recommendations of\u00a0over-the-counter treatments for the common cold &#8211; analysis of prospective cases\u00a0in Poland. BMC Fam Pract. 2021 Oct 30;22(1):216.<\/li>\n<li>Marko M, Pawliczak R. Can we safely use systemic treatment in atopic\u00a0dermatitis during the COVID-19 pandemic? Overview of selected conventional and\u00a0biologic systemic therapies. Expert Rev Clin Immunol. 2021 Jun;17(6):619-627.<\/li>\n<li>Hoffmann A, Kleniewska P, Pawliczak R. Antioxidative activity of probiotics.\u00a0Arch Med Sci. 2019 Nov 21;17(3):792-804.<\/li>\n<li>Pniewska-Dawidczyk E, Kupry\u015b-Lipi\u0144ska I, Turek G, Kacprzak D, Wieczfinska J,\u00a0Kleniewska P, Kuna P, Pawliczak R. Expression of cPLA<sub>2<\/sub>\u03b3 mRNA and\u00a0protein differs the response of PBMC from severe and non-severe asthmatics to\u00a0bacterial lipopolysaccharide and house dust mite allergen. Int J Immunopathol\u00a0Pharmacol. 2021 Jan-Dec;35:2058738421990952.<\/li>\n<li>Banasiak H, Pawliczak R. Clinical profile of chronic bronchial asthma\u00a0patients in Poland: results of the PROKSAL study. Postepy Dermatol Alergol. 2020\u00a0Dec;37(6):879-889.<\/li>\n<li>Kopa PN, Pawliczak R. Menthol additives to tobacco products. Reasons for withdrawing mentholated cigarettes in European Union on 20th may 2020 according to tobacco products\u00a0directive (2014\/40\/EU). Toxicol Mech Methods. 2020 Oct;30(8):555-561.<\/li>\n<li>Wieczfinska J, Sitarek P, Kowalczyk T, Pawliczak R. Leonurus sibiricus root\u00a0extracts decrease airway remodeling markers expression in fibroblasts. Clin Exp\u00a0Immunol. 2020 Oct;202(1):28-46.<\/li>\n<li>Marko M, Pawliczak R. Real-life efficiency and safety comparison study of\u00a0emollient ointment based on glycerophosphoinositol (GPI) salt of choline and\u00a0other emollient products in patients with atopic dermatitis. J Dermatolog Treat.\u00a02020 Aug 4:1-12.<\/li>\n<li>Wieczfinska J, Sitarek P, Kowalczyk T, Ska\u0142a E, Pawliczak R. The anti-inflammatory potential of selected plant-derived compounds in respiratory diseases.\u00a0<i>Curr Pharm Des<\/i>. 2020.<\/li>\n<li>Szymczak-Pajor I, Pawliczak R.\u00a0Comparison of an automated microfluidic immunoassay technology (BioIC, lab-on-chips) and ImmunoCAP assay. Lab-on-chips as a tool for specific IgE (sIgE) detection.\u00a0<i>Postepy Dermatol Alergol<\/i>. 2020;37(1):56\u201060.<\/li>\n<li>Zyma M, Pawliczak R. Characteristics and the role of purinergic receptors in pathophysiology with focus on immune response.\u00a0<i>Int Rev Immunol<\/i>. 2020;39(3):97\u2010117.<\/li>\n<li>Szymczak-Pajor I, Kleniewska P, Wieczfinska J, Pawliczak R. Wide-Range Effects of 1,25(OH)2D3 on Group 4A Phospholipases Is Related to Nuclear Factor \u03ba-B and Phospholipase-A2 Activating Protein Activity in Mast Cells.\u00a0<i>Int Arch Allergy Immunol<\/i>. 2020;181(1):56\u201070.<\/li>\n<li>Kopa PN, Pawliczak R. IQOS &#8211; a heat-not-burn (HnB) tobacco product &#8211; chemical composition and possible impact on oxidative stress and inflammatory response. A systematic review.\u00a0<i>Toxicol Mech Methods<\/i>. 2020;30(2):81\u201087.<\/li>\n<li>\u0141ab\u0119d\u017a N, Pawliczak R. Efficacy and safety of topical calcineurin inhibitors for the treatment of atopic dermatitis: meta-analysis of randomized clinical trials.\u00a0<i>Postepy Dermatol Alergol<\/i>. 2019;36(6):752\u2010759.<\/li>\n<li>Marko M, Pawliczak R. How to interpret the results of comparative drug tests? Statistical analysis methods: standardized SMD mean difference and mean difference calculated by the LSMD least squares method. Polish Journal of Allergology. 2019;6,3: 90\u201399.<\/li>\n<li>Marko M, Pawliczak R. Noninferiority trials in clinical practice. Polish Journal of Allergology. 2019;6,4: 152\u2013159.<\/li>\n<li>Kopa PN, Pawliczak R. Health consequences of smoking \u2013 focusing on alternative smoking methods. Alergologia Polska \u2013 Polish Journal of Allergology. 2019. 3(6): 100-109.<\/li>\n<li>Wieczfinska J, Sitarek P, Ska\u0142a E, Kowalczyk T, Pawliczak R. Inhibition of NADPH Oxidase-Derived Reactive Oxygen Species Decreases Expression of Inflammatory Cytokines in A549 Cells [published correction appears in Inflammation. 2020 Feb 11;:].\u00a0<i>Inflammation<\/i>. 2019;42(6):2205\u20102214.<\/li>\n<li>Kleniewska P, Pawliczak R. The influence of apocynin, lipoic acid and probiotics on antioxidant enzyme levels in the pulmonary tissues of obese asthmatic mice.\u00a0<i>Life Sci<\/i>. 2019;234:116780.<\/li>\n<li>Wieczfi\u0144ska J, Kowalczyk T, Sitarek P, Ska\u0142a E, Pawliczak R.\u00a0Analysis of short-term smoking effects in PBMC of healthy subjects-preliminary study.\u00a0Int J Environ Res Public Health. 2018;\u00a0\u00a0May 18;15(5).<\/li>\n<li>Kleniewska P, Pawliczak R.\u00a0Assessment of human 4-hydroxynonenal, 8-isoprostane concentrations and glutathione reductase activity after synbiotics administration. Adv Med Sci. 2018\u00a0Sep;63(2):301-305.<\/li>\n<li>Szymczak I, Pawliczak R.\u00a0Can vitamin D help in achieving asthma control? Vitamin D &#8222;revisited&#8221;: an updated insight.\u00a0Adv Respir Med<a title=\"Advances in respiratory medicine.\" role=\"menuitem\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Can+vitamin+D+help+in+achieving+asthma+control%3F+Vitamin+D+%22revisited%22%3A+an+updated+insight#\" aria-expanded=\"false\" aria-haspopup=\"true\">.<\/a>2018;86(2):103-109.<\/li>\n<li>Kopa P, Pawliczak R.\u00a0Effect of smoking on gene expression profile &#8211; overall mechanism, impact on respiratory system function, and reference to electronic cigarettes.\u00a0Toxicol Mech Methods.\u00a02018 Jul;28(6):397-409.<\/li>\n<li>Marko M, Pawliczak R.\u00a0Obesity and asthma: risk, control and treatment.\u00a0Postepy Dermatol Alergol.\u00a02018 Dec;35(6):563-571.<\/li>\n<li>Szymczak-Pajor I, Pawliczak R.\u00a0<span class=\"label\">\u00a0<\/span><span class=\"field\">Adipose tissue as a potential source of hormones and cytokines involved in asthma pathogenesis.\u00a0Alergol Pol. 2017. Vol.4. 132-138.<\/span><\/li>\n<li>\u017bebrowska A, Wo\u017aniacka A, Juczy\u0144ska K, Ociepa K, Waszczykowska E, Szymczak I, Pawliczak R.\u00a0Correlation between IL-36\u03b1\u00a0and IL -17 and activity of the disease in selected autoimmune blistering diseases.\u00a0Mediators Inflamm.\u00a02017;2017:8980534.<\/li>\n<li>Juczy\u0144ska K,\u00a0Wo\u017aniacka A,\u00a0Waszczykowska E,\u00a0Danilewicz M,\u00a0Wagrowska-Danilewicz M,\u00a0Wieczfinska J,\u00a0Pawliczak R, \u017bebrowska A.\u00a0 Expression\u00a0of the\u00a0<span class=\"highlight\">JAK\/STAT<\/span>\u00a0<span class=\"highlight\">Signaling Pathway<\/span>\u00a0in\u00a0<span class=\"highlight\">Bullous Pemphigoid<\/span>\u00a0and\u00a0<span class=\"highlight\">Dermatitis Herpetiformis.\u00a0Mediators Inflamm.\u00a02017;2017:6716419.<\/span><\/li>\n<li>Kleniewska P, Pawliczak R.\u00a0Influence of Synbiotics on Selected Oxidative Stress Parameters.\u00a0Oxid Med Cell Longev.\u00a02017;2017:9315375.<\/li>\n<li>Kleniewska P, Pawliczak R.\u00a0The participation of oxidative stress in the pathogenesis of bronchial asthma.\u00a0Biomed Pharmacother.\u00a02017 Oct;94:100-108.<\/li>\n<li>Marko M, Pawliczak R.\u00a0The role of microbiota in allergy development.\u00a0Alergol Pol. 2017; Vol. 4 (2); 58-62.<\/li>\n<li>Wieczfi\u0144ska J, Pawliczak R.\u00a0Thymic stromal lymphopoietin and apocynin alter the expression of airway remodeling factors in human rhinovirus-infected cells.\u00a0Immunobiology.\u00a02017 Aug;222(8-9):892-899.<\/li>\n<li>Luczak E,\u00a0Wieczfinska J,\u00a0Sokolowska M,\u00a0Pniewska E,\u00a0Luczynska D,\u00a0Pawliczak R.\u00a0Troglitazone, a PPAR-gamma agonist, decreases LTC4 concentration in mononuclear cells in patients with asthma.\u00a0Pharmacol Rep.\u00a02017 Dec;69(6):1315-1321.<\/li>\n<li>Kleniewska P, Hoffmann A, Pniewska E, Pawliczak R. The Influence of Probiotic Lactobacillus casei in Combination with Prebiotic Inulin on the Antioxidant Capacity of Human Plasma. Oxid Med Cell Longev. 2016;2016:1340903.<\/li>\n<li>Szymczak I, Pawliczak R. The Active Metabolite of Vitamin D3 as a Potential Immunomodulator. Scand J Immunol. luty 2016;83(2):83\u201391.<\/li>\n<li>Wieczfinska J, Kacprzak D, Pospiech K, Sokolowska M, Nowakowska M, Pniewska E, i in. The whole-genome expression analysis of peripheral blood mononuclear cells from aspirin sensitive asthmatics versus aspirin tolerant patients and healthy donors after in vitro aspirin challenge. Respir Res. 2015;16(1):147.<\/li>\n<li>Kacprzak D, Pawliczak R. Does aspirin-induced oxidative stress cause asthma exacerbation? Arch Med Sci AMS. 19 czerwiec 2015;11(3):494\u2013504.<\/li>\n<li>Pniewska E, Sokolowska M, Kupry\u015b-Lipi\u0144ska I, Kacprzak D, Kuna P, Pawliczak R. Exacerbating factors induce different gene expression profiles in peripheral blood mononuclear cells from asthmatics, patients with chronic obstructive pulmonary disease and healthy subjects. Int Arch Allergy Immunol. 2014;165(4):229\u201343.<\/li>\n<li>Zebrowska A, Wagrowska-Danilewicz M, Danilewicz M, Wieczfinska J, Pniewska E, Zebrowski M, i in. Tissue Factor in Dermatitis Herpetiformis and Bullous Pemphigoid: Link between Immune and Coagulation System in Subepidermal Autoimmune Bullous Diseases. Mediators Inflamm. 2015;2015:870428.<\/li>\n<li>Pniewska E, Sokolowska M, Kupry\u015b-Lipi\u0144ska I, Przybek M, Kuna P, Pawliczak R. The step further to understand the role of cytosolic phospholipase A2 alpha and group X secretory phospholipase A2 in allergic inflammation: pilot study. BioMed Res Int. 2014;2014:670814.<\/li>\n<li>Winiecka-Klimek M, Szybka M, Rieske P, Piaskowski S, Bienkowski M, Walczak M, i in. PIN3 duplication may be partially responsible for TP53 haploinsufficiency. BMC Cancer. 2014;14:669.<\/li>\n<li>Wieczfinska J, Sokolowska M, Pawliczak R. NOX Modifiers-Just a Step Away from Application in the Therapy of Airway Inflammation? Antioxid Redox Signal. 10 sierpie\u0144 2015;23(5):428\u201345.<\/li>\n<li>Pniewska E, Pawliczak R. The involvement of phospholipases A2 in asthma and chronic obstructive pulmonary disease. Mediators Inflamm. 2013;2013:793505.<\/li>\n<li>Mokrowiecka A, Sokolowska M, Luczak E, Dudojc M, Wieczfinska J, Kacprzak D, i in. Adiponectin and leptin receptors expression in Barrett\u2019s esophagus and normal squamous epithelium in relation to central obesity status. J Physiol Pharmacol Off J Pol Physiol Soc. kwiecie\u0144 2013;64(2):193\u20139.<\/li>\n<li>Pawliczak R. New horizons in allergy diagnostics and treatment. Pol Arch Med Wewn\u0119trznej. 2013;123(5):246\u201350.<\/li>\n<li>Zebrowska A, Wagrowska-Danilewicz M, Danilewicz M, Sokolowska M, Stasikowska-Kawecka O, Erkiert-Polguj A, i in. Does Adam17 cause the destruction of anchoring fibers via shedding tumor necrosis factor \u03b1 in bullous pemphigoid and dermatitis herpetiformis? J Cutan Med Surg. czerwiec 2012;16(3):149\u201350.<\/li>\n<li>Stefanska J, Sarniak A, Wlodarczyk A, Sokolowska M, Doniec Z, Bialasiewicz P, i in. Hydrogen peroxide and nitrite reduction in exhaled breath condensate of COPD patients. Pulm Pharmacol Ther. pa\u017adziernik 2012;25(5):343\u20138.<\/li>\n<li>Stefanska J, Sarniak A, Wlodarczyk A, Sokolowska M, Pniewska E, Doniec Z, i in. Apocynin reduces reactive oxygen species concentrations in exhaled breath condensate in asthmatics. Exp Lung Res. marzec 2012;38(2):90\u20139.<\/li>\n<li>Adamusiak AM, Stasikowska-Kanicka O, Lewandowska-Polak A, Danilewicz M, Wagrowska-Danilewicz M, Jankowski A, i in. Expression of arachidonate metabolism enzymes and receptors in nasal polyps of aspirin-hypersensitive asthmatics. Int Arch Allergy Immunol. 2012;157(4):354\u201362.<\/li>\n<li>Lesiak A, Narbutt J, Wodz K, Pawliczak R, Rogowski-Tylman M, Sysa-Jedrzejowska A, i in. Repeated suberythemal UVB preexposure protects against high-dose UVB-induced expression of vitamin D receptor protein in human Skin. J Invest Dermatol. listopad 2011;131(11):2332\u20135.<\/li>\n<li>Lesiak A, Norval M, Wodz-Naskiewicz K, Pawliczak R, Rogowski-Tylman M, Sysa-Jedrzejowska A, i in. An enhanced risk of basal cell carcinoma is associated with particular polymorphisms in the VDR and MTHFR genes. Exp Dermatol. pa\u017adziernik 2011;20(10):800\u20134.<\/li>\n<li>Sokolowska M, Stefanska J, Wodz-Naskiewicz K, Pawliczak R. Cytosolic phospholipase A2 group IVA influence on GM-CSF expression in human lung cells: a pilot study. Med Sci Monit Int Med J Exp Clin Res. wrzesie\u0144 2010;16(9):BR300-306.<\/li>\n<li>Sokolowska M, Stefanska J, Wodz-Naskiewicz K, Cieslak M, Pawliczak R. Cytosolic phospholipase A2 group IVA is overexpressed in patients with persistent asthma and regulated by the promoter microsatellites. J Allergy Clin Immunol. czerwiec 2010;125(6):1393\u20135.<\/li>\n<li>Sokolowska M, Wodz-Naskiewicz K, Cieslak M, Seta K, Bednarek AK, Pawliczak R. Variable expression of cysteinyl leukotriene type I receptor splice variants in asthmatic females with different promoter haplotypes. BMC Immunol. 2009;10:63.<\/li>\n<li>Stefanska J, Sokolowska M, Sarniak A, Wlodarczyk A, Doniec Z, Nowak D, i in. Apocynin decreases hydrogen peroxide and nitrate concentrations in exhaled breath in healthy subjects. Pulm Pharmacol Ther. luty 2010;23(1):48\u201354.<\/li>\n<li>Zebrowska A, Wagrowska-Danilewicz M, Danilewicz M, Wodz K, Sokolowska M, Erkiert-Polguj A, i in. Expression of selected ADAMs in bullous pemphigoid and dermatitis herpetiformis. J Dermatol Sci. pa\u017adziernik 2009;56(1):58\u201361.<\/li>\n<li>Zebrowska A, Waszczykowska E, Wagrowska-Danilewicz M, Danilewicz M, Erkiert-Polguj A, Pawliczak R, i in. Expression of selected adhesion molecules in dermatitis herpetiformis and bullous pemphigoid. Pol J Pathol Off J Pol Soc Pathol. 2009;60(1):26\u201334.<\/li>\n<li>W\u00f3dz-Naskiewicz K, Pawliczak R. [Cysteinyl leukotrienes and their receptors]. Postepy Biochem. 2009;55(4):395\u2013405.<\/li>\n<li>Stefanska J, Pawliczak R. Apocynin: molecular aptitudes. Mediators Inflamm. 2008;2008:106507.<\/li>\n<li>Jaworek R, Pawliczak R, Miedzobrodzki J. [Recent opinions on the role of acidophilic granulocytes in mechanisms of immunological defence and in pathogenesis of selected human diseases]. Folia Med Cracov. 2008;49(3\u20134):13\u201322.<\/li>\n<li>Sokolowska M, Borowiec M, Ptasinska A, Cieslak M, Shelhamer JH, Kowalski ML, i in. 85-kDa cytosolic phospholipase A2 group IValpha gene promoter polymorphisms in patients with severe asthma: a gene expression and case-control study. Clin Exp Immunol. pa\u017adziernik 2007;150(1):124\u201331.<\/li>\n<li>Kowalski ML, Borowiec M, Kurowski M, Pawliczak R. Alternative splicing of cyclooxygenase-1 gene: altered expression in leucocytes from patients with bronchial asthma and association with aspirin-induced 15-HETE release. Allergy. czerwiec 2007;62(6):628\u201334.<\/li>\n<li>Lewandowicz AM, Pawliczak R. [Arginine metabolism in bronchial asthma]. Post\u0229py Hig Med Do\u015bw Online. 2007;61:156\u201366.<\/li>\n<li>Woszczek G, Chen L-Y, Nagineni S, Alsaaty S, Harry A, Logun C, i in. IFN-gamma induces cysteinyl leukotriene receptor 2 expression and enhances the responsiveness of human endothelial cells to cysteinyl leukotrienes. J Immunol Baltim Md 1950. 15 kwiecie\u0144 2007;178(8):5262\u201370.<\/li>\n<li>Soko\u0142owska M, Kowalski ML, Pawliczak R. [Peroxisome proliferator-activated receptors-gamma (PPAR-gamma) and their role in immunoregulation and inflammation control]. Post\u0229py Hig Med Do\u015bw Online. 2005;59:472\u201384.<\/li>\n<li>Pawliczak R, Lewandowska-Polak A, Kowalski ML. Pathogenesis of nasal polyps: an update. Curr Allergy Asthma Rep. listopad 2005;5(6):463\u201371.<\/li>\n<li>Woszczek G, Pawliczak R, Qi H-Y, Nagineni S, Alsaaty S, Logun C, i in. Functional characterization of human cysteinyl leukotriene 1 receptor gene structure. J Immunol Baltim Md 1950. 15 pa\u017adziernik 2005;175(8):5152\u20139.<\/li>\n<li>Woszczek G, Borowiec M, Ptasinska A, Kosinski S, Pawliczak R, Kowalski ML. Beta2-ADR haplotypes\/polymorphisms associate with bronchodilator response and total IgE in grass allergy. Allergy. listopad 2005;60(11):1412\u20137.<\/li>\n<li>Kowalski ML, Ptasinska A, Jedrzejczak M, Bienkiewicz B, Cieslak M, Grzegorczyk J, i in. Aspirin-triggered 15-HETE generation in peripheral blood leukocytes is a specific and sensitive Aspirin-Sensitive Patients Identification Test (ASPITest). Allergy. wrzesie\u0144 2005;60(9):1139\u201345.<\/li>\n<li>Pawliczak R, Logun C, Madara P, Barb J, Suffredini AF, Munson PJ, i in. Influence of IFN-gamma on gene expression in normal human bronchial epithelial cells: modulation of IFN-gamma effects by dexamethasone. Physiol Genomics. 21 wrzesie\u0144 2005;23(1):28\u201345.<\/li>\n<li>Kowalski ML, Lewandowska-Polak A, Wo\u017aniak J, Ptasi\u0144ska A, Jankowski A, Wagrowska-Danilewicz M, i in. Association of stem cell factor expression in nasal polyp epithelial cells with aspirin sensitivity and asthma. Allergy. maj 2005;60(5):631\u20137.<\/li>\n<li>Soko\u0142owska M, Kowalski ML, Pawliczak R. [Cysteinyl leukotriene receptors]. Postepy Biochem. 2004;50(2):131\u201343.<\/li>\n<li>Cowan MJ, Yao X-L, Pawliczak R, Huang X, Logun C, Madara P, i in. The role of TFIID, the initiator element and a novel 5\u2019 TFIID binding site in the transcriptional control of the TATA-less human cytosolic phospholipase A2-alpha promoter. Biochim Biophys Acta. 5 listopad 2004;1680(3):145\u201357.<\/li>\n<li>Lewandowicz AM, Kowalski ML, Pawliczak R. [RGS proteins (regulators of G protein signaling) and their roles in regulation of immune response]. Post\u0229py Hig Med Do\u015bw Online. 2004;58:312\u201320.<\/li>\n<li>Pawliczak R, Logun C, Madara P, Lawrence M, Woszczek G, Ptasinska A, i in. Cytosolic phospholipase A2 Group IValpha but not secreted phospholipase A2 Group IIA, V, or X induces interleukin-8 and cyclooxygenase-2 gene and protein expression through peroxisome proliferator-activated receptors gamma 1 and 2 in human lung cells. J Biol Chem. 19 listopad 2004;279(47):48550\u201361.<\/li>\n<li>Pawliczak R, Kowalski ML. [X-linked agammaglobulinemia: an update]. Pol Merkur Lek Organ Pol Tow Lek. grudzie\u0144 2003;15(90):592\u20139.<\/li>\n<li>Woszczek G, Pawliczak R, Kowalski ML. [Leukotrienes as inflammation mediators]. Post\u0229py Hig Med Do\u015bw. 2003;57(5):593\u2013610.<\/li>\n<li>Pawliczak R. [The role of radical oxygen species in airway inflammation]. Pol Merkur Lek Organ Pol Tow Lek. czerwiec 2003;14(84):493\u20136.<\/li>\n<li>Pawliczak R, Shelhamer JH. Application of functional genomics in allergy and clinical immunology. Allergy. pa\u017adziernik 2003;58(10):973\u201380.<\/li>\n<li>Kowalski ML, Ptasinska A, Bienkiewicz B, Pawliczak R, DuBuske L. Differential effects of aspirin and misoprostol on 15-hydroxyeicosatetraenoic acid generation by leukocytes from aspirin-sensitive asthmatic patients. J Allergy Clin Immunol. wrzesie\u0144 2003;112(3):505\u201312.<\/li>\n<li>Huang X, Pawliczak R, Yao X-L, Madara P, Alsaaty S, Shelhamer JH, i in. Characterization of the human p11 promoter sequence. Gene. 22 maj 2003;310:133\u201342.<\/li>\n<li>Pawliczak R. [Common variable immunodeficiency&#8211;advances in diagnosis, pathogenesis and treatment]. Pol Merkur Lek Organ Pol Tow Lek. stycze\u0144 2003;14(79):73\u20138.<\/li>\n<li>Huang X, Pawliczak R, Yao X, Cowan MJ, Gladwin MT, Walter MJ, i in. Interferon-gamma induces p11 gene and protein expression in human epithelial cells through interferon-gamma-activated sequences in the p11 promoter. J Biol Chem. 14 marzec 2003;278(11):9298\u2013308.<\/li>\n<li>Nanavaty UB, Pawliczak R, Doniger J, Gladwin MT, Cowan MJ, Logun C, i in. Oxidant-induced cell death in respiratory epithelial cells is due to DNA damage and loss of ATP. Exp Lung Res. grudzie\u0144 2002;28(8):591\u2013607.<\/li>\n<li>Pawliczak R, Huang X-L, Nanavaty UB, Lawrence M, Madara P, Shelhamer JH. Oxidative stress induces arachidonate release from human lung cells through the epithelial growth factor receptor pathway. Am J Respir Cell Mol Biol. grudzie\u0144 2002;27(6):722\u201331.<\/li>\n<li>Pawliczak R, Kowalski ML. [Analysis of gene expression at the entire genome scale&#8211;applications in biological sciences and medicine]. Post\u0229py Hig Med Do\u015bw. 2002;56(4):537\u201353.<\/li>\n<li>Huang X-L, Pawliczak R, Cowan MJ, Gladwin MT, Madara P, Logun C, i in. Epidermal growth factor induces p11 gene and protein expression and down-regulates calcium ionophore-induced arachidonic acid release in human epithelial cells. J Biol Chem. 11 pa\u017adziernik 2002;277(41):38431\u201340.<\/li>\n<li>Pawliczak R, Han C, Huang X-L, Demetris AJ, Shelhamer JH, Wu T. 85-kDa cytosolic phospholipase A2 mediates peroxisome proliferator-activated receptor gamma activation in human lung epithelial cells. J Biol Chem. 6 wrzesie\u0144 2002;277(36):33153\u201363.<\/li>\n<li>Kowalski ML, Grzegorczyk J, Pawliczak R, Kornatowski T, Wagrowska-Danilewicz M, Danilewicz M. Decreased apoptosis and distinct profile of infiltrating cells in the nasal polyps of patients with aspirin hypersensitivity. Allergy. czerwiec 2002;57(6):493\u2013500.<\/li>\n<li>Pawliczak R, Cowan MJ, Huang X, Nanavaty UB, Alsaaty S, Logun C, i in. p11 expression in human bronchial epithelial cells is increased by nitric oxide in a cGMP-dependent pathway involving protein kinase G activation. J Biol Chem. 30 listopad 2001;276(48):44613\u201321.<\/li>\n<li>Kowalski ML, Pawliczak R, Wozniak J, Siuda K, Poniatowska M, Iwaszkiewicz J, i in. Differential metabolism of arachidonic acid in nasal polyp epithelial cells cultured from aspirin-sensitive and aspirin-tolerant patients. Am J Respir Crit Care Med. luty 2000;161(2 Pt 1):391\u20138.<\/li>\n<li>Grzegorczyk J, Kowalski ML, Kornatowski T, Pawliczak R. Expression of cyclooxygenase in nasal polyps from atopic and nonatopic subjects. J Investig Allergol Clin Immunol. grudzie\u0144 1999;9(6):380\u20135.<\/li>\n<li>Pawliczak R, Kowalski ML. [Metabolites of arachidonic acid (eicosanoids) in the airways&#8211;the role of epithelium in synthesis of eicosanoids]. Post\u0229py Hig Med Do\u015bw. 1998;52(2):187\u201399.<\/li>\n<li>Kowalski ML, Pawliczak R, Wo\u017aniak J, Siuda K, Grzegorczyk J, Pietrzak M, i in. Culture of human nasal epithelial cells from nasal polyps on collagen matrix. Arch Immunol Ther Exp (Warsz). 1998;46(1):51\u20137.<\/li>\n<li>Pawliczak R, Kowalski ML, Danilewicz M, Wagrowska-Danilewicz M, Lewandowski A. Distribution of mast cells and eosinophils in nasal polyps from atopic and nonatopic subjects: a morphometric study. Am J Rhinol. sierpie\u0144 1997;11(4):257\u201362.<\/li>\n<li>Pawliczak R, Kowalski ML. [Allergic inflammation&#8211;participation and role of adhesion molecules]. Post\u0229py Hig Med Do\u015bw. 1997;51(1):39\u201353.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Kontakt rafal.pawliczak@csk.umed.lodz.pl Wykszta\u0142cenie 1993 \u2013dyplom z wyr\u00f3\u017cnieniem i tytu\u0142 zawodowy lekarza, Uniwersytet Medyczny w \u0141odzi 1999 \u2013 doktor nauk medycznych, Wydzia\u0142 Lekarski, Akademia Medyczna w \u0141odzi Tytu\u0142 pracy: ,,Por\u00f3wnanie metabolizmu kwasu arachidonowego w hodowlach kom\u00f3rek nab\u0142onk\u00f3w g\u00f3rnych dr\u00f3g oddechowych u chorych na astm\u0119 z nadwra\u017cliwo\u015bci\u0105 na aspiryn\u0119 i u os\u00f3b dobrze toleruj\u0105cych niesteroidowe leki przeciwzapalne\u2019\u2019&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":10,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-35","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/zimp.umed.pl\/index.php\/wp-json\/wp\/v2\/pages\/35","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zimp.umed.pl\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/zimp.umed.pl\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/zimp.umed.pl\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/zimp.umed.pl\/index.php\/wp-json\/wp\/v2\/comments?post=35"}],"version-history":[{"count":32,"href":"https:\/\/zimp.umed.pl\/index.php\/wp-json\/wp\/v2\/pages\/35\/revisions"}],"predecessor-version":[{"id":699,"href":"https:\/\/zimp.umed.pl\/index.php\/wp-json\/wp\/v2\/pages\/35\/revisions\/699"}],"up":[{"embeddable":true,"href":"https:\/\/zimp.umed.pl\/index.php\/wp-json\/wp\/v2\/pages\/10"}],"wp:attachment":[{"href":"https:\/\/zimp.umed.pl\/index.php\/wp-json\/wp\/v2\/media?parent=35"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}